2018-11-19 19:32:222025-04-14 01:53:07
description
C-terminal part of the split gene spsM (together with [[gene|yodU]]), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage
C-terminal part of the split gene spsM (together with [[gene|yodU]]), legionaminic acid synthesis, in B. subtilis 168 the gene is disrupted by the [[category|SP-beta prophage]]
locus
BSU21670
BSU_21670
function
spore envelope polysaccharide biosynthesis
legionaminic acid synthesis
product
unknown
UDP-NAcGlcA inverting 4,6-dehydratase (C-terminal part)
outlinks
bsu
BSU21670
BSU_21670
The protein
Structure
[PDB|6BWC] (from B. thuringiensis, 39% identity)
[PDB|6BWC] (from B. thuringiensis, 39% identity) [pubmed|29266550]
The protein
[SW|Localization]
cell membrane (according to Swiss-Prot)
References
Gene
Phenotypes of a mutant
the [[gene|ypqP]] mutant of PY79 has a less hydrophobic spore surface [pubmed|32817102]
The protein
Catalyzed reaction/ biological activity
SpsM catalyzes the C-4/C-6 dehydration of the UDP-GlcNAc to produce UDP-4-keto-6-deoxy-GlcNAc, this is the first reaction of the legionaminic acid biosynthesis pathway [pubmed|32817102]
required for spore crust assembly, legionaminic acid synthesis [pubmed|32817102]